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Details:

The rise in antibiotic resistance in Gram-negative bacteria is a remarkable example of how bacteria can receive, use and pass on new genetic information that leads to resistance to one or more antibiotics. The types of resistance found vary. Overall, however, it appears that resistances to quinolones and broad-spectrum ß-lactams in the Enterobacteriaceae family and in Acinetobacter spp. is becoming established and widespread. In addition, the options for treating Pseudomonas aeruginosa infections are increasingly limited. Although the introduction of carbapenems in the 1980s promised a new, permanent treatment option for severe bacterial infections, today an
increasing carbapenem resistance can be observed in Enterobacteriaceae and Acinetobacter spp. In P. aeruginosa, it is virtually commonplace.